StorageReview checked out the WD Gold 22TB and Synology DiskStation DS1821+
A quote from the article:
Back in August, we reviewed the WD Gold 22TB CMR HDD, which was highlighted by OptiNAND-enabled ArmorCache technology. We previously tested the Golds via our 36-bay Supermicro Storage SuperServer (SSG-540P-E1CTR36H) with TrueNAS installed (RAID2Z); however, we wanted to gauge the performance (and value) of the 22TB Golds when used in an SMB environment. For this review, we will be looking at how well they fare inside a Synology DiskStation DS1821+.WD Gold 22TB and Synology DiskStation DS1821+ Review