For playing games, I typically play a wide range from RTS to FPS within just a few hours. For the last two years I've been using a Razer Deathadder, which has the same basic layout with only two extra buttons on the side. What was surprising is that I couldn't tell the difference between the Talon and that $60 mouse. In fact, the Razer options is completely controlled in software so I am usually unable to change the DPI, since I don't have time or want to download and install software across on my computers and laptop. Having a button right on top to toggle between DPI presets made switching from playing Starcraft to using the Railgun in Unreal Tournament painless. Overall, I would use this mouse for gaming and not think twice about another one.