New in Release 320.00:

ODE Driver
The R319 drivers are the fifth ‘Optimal Drivers for Enterprise’, a release dedicated to relatively long term stability for ISV certification, OEMs, and Enterprise customers.
Workstation Features
NVIDIA Control Panel
Display Category - Set up Multiple Displays Page Lock Clone Region control - new control lets you specify a section of a "pan and scan clone" source display to be cloned and locked. Once locked, you cannot dynamically pan the area.
Pan and Scan Clone were introduced in R300 drivers. It is similar to regular Clone mode except that the two displays are different resolutions. The display with the larger resolution is the source clone display. The display with the smaller resolution shows a cropped section of the cloned source display.
NVIDIA Control Panel -> Workstation Category -> Set Up Mosaic Page --Control Display - You can now set up a control display that is separate from the Mosaic configuration
Multiple Mosaic Groups
Provides multiple Mosaic/Premium Mosaic topologies to be active on a single system. Configurable using the ConfigureMosaic tool.
GPUDirect for Video - improved GPUDirect for Video performance on Premium Mosaic configurations.
New NVIEW version - 140.54
Revised the UI to incorporate a navigation tree instead of tabs.
New Bird's Eye View starting page
New Grid Line Editor controls
NvWMI 2.12
NvWMI is a WMI-based interface for configuring enterprise systems.
Added support for Quadro Sync.
Added support for GPU Power Management --Added method to query the serial number of a board
NvAPI
Added APIs to configure sync delay (skew and start delay) in lines and pixels.
Workstation application compatibility fixes. Please read the release notes for more information on product support, feature limitations, driver fixes and known compatibility issues.
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Existing Support:

Support for CUDA 5.0
Support for OpenGL 4.3
Support for the Open Computing Language (OpenCL) 1.1 in Quadro FX Series x700 and newer as well as the FX4600 and FX5600
Support for DirectX11