G'MIC is an open and full-featured framework for image processing in Gimp, Paint.Net, and Krita.

You have several different user interfaces in G'MIC that will convert/manipulate/filter/visualize generic image datasets, from 1d scalar signals to 3d+t sequences of multi-spectral volumetric images.

Various plug-ins are also available at the author's site.

G'MIC Features:

A portable and thread-safe C++ library 'libgmic' for generic image processing, embeddable in third-party applications.
A command line interface 'gmic' to perform image processing operations from a shell.
An easy-to-use plug-in 'gmic_gimp' which adds hundreds of new filters to GIMP
A web service, 'G'MIC Online,' to apply image filters directly on a web browser.
A Qt-based interface 'Zart' for real-time manipulation of webcam images.
A complete script language to develop your own complex image processing pipelines.

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