PC World posted a review on the Evoluent VerticalMouse C Right Wireless Mouse
A quote from the article:
The Evoluent VerticalMouse C Right Wireless ($109.95) was designed combat repetitive strain injury (RSI) and other shoulder-arm-hand discomforts, at least for the 90 percent of us that are right-hand dominant. The company claims the palm-down position used to operate conventional mice twists your forearm and puts you at risk of injury over time. The VerticalMouse C Right Wireless puts your arm in the more “neutral”—and presumably safer—handshake grip position.Evoluent VerticalMouse C Right Wireless Review
I have to admit I couldn’t find any data to support this idea, though, and easily found plenty to contradict it. By most expert-y accounts, the handshake grip is not a neutral position and the proper hand and wrist Position for using a mouse is, in fact, pretty much the one Evoluent claims is the problem.