From everyone here at Piriform, the company that brought you CCleaner and Recuva... we now bring you a file defragmentation tool... Defraggler!
It differs from other defrag tools on the market, by enabling you to quickly and simply defrag the files you want to, without having to process the whole drive. Simply run it, select the file and defragment in seconds. No more struggling with the Windows defragmentation tool!

And remember like all Piriform products, Defraggler is completely free for both corporate and individual use.
What's New in version 1.10.143:

Added file exclusion feature.
Added detection of Solid State Drives.
Added "Include non-fragmented files" checkbox to file search.
Improved interactivity of search.
Fixed problem that could allow df.exe and Defraggler.exe to run at the same time.
Fixed rare crash while reanalyzing.
Minor GUI text changes.
Minor bug fixes.